Structure of PDB 7usp Chain B

Receptor sequence
>7uspB (length=91) Species: 9606 (Homo sapiens) [Search protein sequence]
KIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHI
LTRVNRKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFY
3D structure
PDB7usp Characterization of caspase-2 inhibitors based on specific sites of caspase-2-mediated proteolysis.
ChainB
Resolution2.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.56: caspase-3.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y204 S205 W206 R207 N208 S209 S249 F250 F252 F256 Y19 S20 W21 R22 N23 S24 S64 F65 F67 F71
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7usp, PDBe:7usp, PDBj:7usp
PDBsum7usp
PubMed35642311
UniProtP42574|CASP3_HUMAN Caspase-3 (Gene Name=CASP3)

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