Structure of PDB 7uj1 Chain B

Receptor sequence
>7uj1B (length=270) Species: 9606 (Homo sapiens) [Search protein sequence]
SDSEGFKANLSLLRRPGEKTYTQRCRLFVGNLPADITEDEFKRLFAKYGE
PGEVFINKGKGFGFIKLESRALAEIAKAELDDTPMRGRQLRVRFATHAAA
LSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDRGRSTGKGIVEFASKP
AARKAFERCSEGVFLLTTTPRPVIVEPLEQLDDEDGLPEKLAQKNPMYQK
ERETPPRFAQHGTFEYEYSQRWKSLDEMEKQQREQVEKNMKDAKDKLESE
MEDAYHEHQANLLRQDLMRR
3D structure
PDB7uj1 Insight into the Tumor Suppression Mechanism from the Structure of Human Polypyrimidine Splicing Factor (PSF/SFPQ) Complexed with a 30mer RNA from Murine Virus-like 30S Transcript-1.
ChainB
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B F300 N303 F327 K332 F334 F336 R360 Q361 R365 A367 T368 K466 F28 N31 F55 K60 F62 F64 R88 Q89 R93 A95 T96 K194
BS02 rna B R407 R409 R135 R137
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:7uj1, PDBe:7uj1, PDBj:7uj1
PDBsum7uj1
PubMed35998361
UniProtP23246|SFPQ_HUMAN Splicing factor, proline- and glutamine-rich (Gene Name=SFPQ)

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