Structure of PDB 7uby Chain B

Receptor sequence
>7ubyB (length=529) Species: 1496 (Clostridioides difficile) [Search protein sequence]
SLISKEELIKLAEYKTILTNLDEYNKLTTNNNENKYLQLKKLNESIDVFM
NKYKSRNRALSNLKKDILKEVILIKNSNTSPVEKNLHFVWIGGEVSDIAL
EYIKQWADINAEYNIKLWYDSEAFLVNTLKKAIVESSTTEALQLLEEEIQ
NPQFDNMKFYKKRMEFIYDRQKRFINYYASQINKPTVPTIDDIIKSHLVS
EYNRDETVLESYRTNSLRKINSNHGIDIRANSLFTEQELLNIYSQELLNR
GNLAAASDIVRLLALKNFGGVYLDVDMLPGIHSDLFKTISRPSSIGLDRW
EMIKLEAIMKYKKYINNYTSENFDKLDQQLKDNFKLIIESKKSEIFSKLE
NLNVSDLEIKIAFALGSVINQALISKQGSYLTNLVIEQVKNRYQFLNQHL
NPAIESDNNFTDTTKIFHDSLFNSATAENSMFLTKIAPYLQVGFMPEARS
TISLSGPGAYASAYYDFINLQENTIEKTLKASDLIEFKFPENNLSQLTEQ
EINSLWSFDQASAKYQFEKYVRDYTGGSL
3D structure
PDB7uby Neutralizing epitopes on Clostridioides difficile toxin A revealed by the structures of two camelid VHH antibodies.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.-
3.4.22.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UPG B V100 W101 I102 N138 L264 S268 D269 R272 D285 N383 S517 L518 W519 V89 W90 I91 N127 L253 S257 D258 R261 D274 N370 S504 L505 W506
BS02 MN B D287 E514 D276 E501
Gene Ontology
Molecular Function
GO:0016757 glycosyltransferase activity

View graph for
Molecular Function
External links
PDB RCSB:7uby, PDBe:7uby, PDBj:7uby
PDBsum7uby
PubMed36466927
UniProtP16154|TCDA_CLODI Toxin A (Gene Name=tcdA)

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