Structure of PDB 7u60 Chain B

Receptor sequence
>7u60B (length=464) Species: 9606 (Homo sapiens) [Search protein sequence]
NICTTRGVSSCQQCLAVSPMCAWCSDEALPLGSPRCDLKENLLKDNCAPE
SIEFPVSEARVLEDRPLSDKGSGDSSQVTQVSPQRIALRLRPDDSKNFSI
QVRQVEDYPVDIYYLMDLSYSMKDDLWSIQNLGTKLATQMRKLTSNLRIG
FGAFVDKPVSPYMYISPPEALENPCYDMKTTCLPMFGYKHVLTLTDQVTR
FNEEVKKQSVSRNRDAPEGGFDAIMQATVCDEKIGWRNDASHLLVFTTDA
KTHIALDGRLAGIVQPNDGQCHVGSDNHYSASTTMDYPSLGLMTEKLSQK
NINLIFAVTENVVNLYQNYSELIPGTTVGVLSMDSSNVLQLIVDAYGKIR
SKVELEVRDLPEELSLSFNATCLNNEVIPGLKSCMGLKIGDTVSFSIEAK
VRGCPQEKEKSFTIKPVGFKDSLIVQVTFDCDCACQAQAEPNSHRCNNGN
GTFECGVCRCGPGW
3D structure
PDB7u60 A general chemical principle for creating closure-stabilizing integrin inhibitors.
ChainB
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B S121 Y122 S123 N215 R216 A218 E220 S119 Y120 S121 N213 R214 A216 E218
BS02 MN B S121 S123 E220 S119 S121 E218
BS03 MN B D126 D127 M335 D124 D125 M333
BS04 MN B D158 N215 D217 P219 E220 D156 N213 D215 P217 E218
External links
PDB RCSB:7u60, PDBe:7u60, PDBj:7u60
PDBsum7u60
PubMed36113427
UniProtP05106|ITB3_HUMAN Integrin beta-3 (Gene Name=ITGB3)

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