Structure of PDB 7u35 Chain B

Receptor sequence
>7u35B (length=437) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
HHFRIVVGLGKSGMSLVRYLARRGLPFAVVDTRENPPELATLRAQYPQVE
VRCGELDAEFLCSARELYVSPGLSLRTPALVQAAAKGVRISGDIDLFARE
AKAPIVAITGSNAKSTVTTLVGEMAVAADKRVAVGGNLGTPALDLLADDI
ELYVLELSSFQLETCDRLNAEVATVLNVSEDHMMADYHLAKHRIFRGARQ
VVVNRADALTRPLIADTVPCWSFGLNKPDFKAFGLIEEDGQKWLAFQFDK
LLPVGELKIRGAHNYSNALAALALGHAVGLPFDAMLGALKAFSGLAHRCQ
WVRERQGVSYYDDSKATNVGAALAAIEGLGADIDGKLVLLAGGDGKGADF
HDLREPVARFCRAVVLLGRDAGLIAQALGNAVPLVRVATLDEAVRQAAEL
AREGDAVLLSPACASLDMFKNFEERGRLFAKAVEELA
3D structure
PDB7u35 Crystal Structure of UDP-N-acetylmuramoylalanine--D-glutamate ligase (MurD) from Pseudomonas aeruginosa PAO1 in complex with ADP
ChainB
Resolution1.95 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 6.3.2.9: UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B N118 A119 K120 S121 T122 H274 N278 R309 D324 K326 A327 A332 A335 N112 A113 K114 S115 T116 H263 N267 R298 D313 K315 A316 A321 A324
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008764 UDP-N-acetylmuramoylalanine-D-glutamate ligase activity
GO:0016874 ligase activity
GO:0016881 acid-amino acid ligase activity
Biological Process
GO:0008360 regulation of cell shape
GO:0009058 biosynthetic process
GO:0009252 peptidoglycan biosynthetic process
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7u35, PDBe:7u35, PDBj:7u35
PDBsum7u35
PubMed
UniProtQ9HVZ9|MURD_PSEAE UDP-N-acetylmuramoylalanine--D-glutamate ligase (Gene Name=murD)

[Back to BioLiP]