Structure of PDB 7u0o Chain B

Receptor sequence
>7u0oB (length=268) Species: 1766 (Mycolicibacterium fortuitum) [Search protein sequence]
AGLLEGKRILVTGIITDSSIAFHIAKVAQEAGAELVLTGFDRMKLIQRIA
DRLPKPAPLLELDVQNEEHLASLADRISGAIGEGNKLDGVVHSIGFMPQT
GMGVNPFFDAPYADVAKGIHISAYSYASLAKATLPIMNEGGSIVGMDFDP
TRAMPAYNWMTVAKSALESVNRFVAREAGAAGVRSNLVAAGPIRTLAMSA
IVGGALGDEAGKQMQLLEEGWDQRAPIGWNMKDPTPVAKTVCALLSDWMP
ATTGTIIYADGGASTQLL
3D structure
PDB7u0o In Vitro and In Vivo Efficacy of NITD-916 against Mycobacterium fortuitum.
ChainB
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.1.9: enoyl-[acyl-carrier-protein] reductase (NADH).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAD B G14 I15 I16 S20 I21 F41 D64 V65 S94 I95 I122 M147 D148 F149 K165 A191 P193 I194 G13 I14 I15 S19 I20 F40 D63 V64 S93 I94 I121 M146 D147 F148 K164 A190 P192 I193
BS02 3KY B G96 Y158 M199 G95 Y157 M198
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004318 enoyl-[acyl-carrier-protein] reductase (NADH) activity
GO:0016491 oxidoreductase activity
Biological Process
GO:0006633 fatty acid biosynthetic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7u0o, PDBe:7u0o, PDBj:7u0o
PDBsum7u0o
PubMed36920188
UniProtA0A0N9XSE6

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