Structure of PDB 7tmm Chain B

Receptor sequence
>7tmmB (length=464) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
NKKAVEQGFNVKPRLNYNTVSGVNGPLVILEKVKFPRYNEIVNLTLPDGT
VRQGQVLEIRGDRAIVQVFEGTSGIDVKKTTVEFTGESLRIPVSEDMLGR
IFDGSGRPIDNGPKVFAEDYLDINGSPINPYARIYPEEMISTGVSAIDTM
NSIARGQKIPIFSASGLPHNEIAAQICRQAGLVRPNFSIVFAAMGVNLET
ARFFKQDFEENGSLERTSLFLNLANDPTIERIITPRLALTTAEYLAYQTE
RHVLTILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLSTIYERAGR
VEGRNGSITQIPILTMPNDDITHPIPDLTGYITEGQIFVDRQLHNKGIYP
PINVLPSLSRLMKSAIGEGMTRKDHGDVSNQLYAKYAIGKDAAAMKAVVG
EEALSIEDKLSLEFLEKFEKTFITQGAYEDRTVFESLDQAWSLLRIYPKE
MLNRISPKILDEFY
3D structure
PDB7tmm Coordinated conformational changes in the V 1 complex during V-ATPase reversible dissociation.
ChainB
Resolution3.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B R381 K384 R360 K363
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0046961 proton-transporting ATPase activity, rotational mechanism
Biological Process
GO:0000425 pexophagy
GO:0006874 intracellular calcium ion homeostasis
GO:0007035 vacuolar acidification
GO:0046034 ATP metabolic process
GO:0048388 endosomal lumen acidification
GO:0055085 transmembrane transport
GO:0061795 Golgi lumen acidification
GO:1902600 proton transmembrane transport
GO:1902906 proteasome storage granule assembly
Cellular Component
GO:0000139 Golgi membrane
GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain
GO:0000329 fungal-type vacuole membrane
GO:0005737 cytoplasm
GO:0005773 vacuole
GO:0005774 vacuolar membrane
GO:0010494 cytoplasmic stress granule
GO:0016020 membrane
GO:0016471 vacuolar proton-transporting V-type ATPase complex
GO:0033176 proton-transporting V-type ATPase complex
GO:0033180 proton-transporting V-type ATPase, V1 domain
GO:0045121 membrane raft
GO:1990816 vacuole-mitochondrion membrane contact site

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7tmm, PDBe:7tmm, PDBj:7tmm
PDBsum7tmm
PubMed35469063
UniProtP16140|VATB_YEAST V-type proton ATPase subunit B (Gene Name=VMA2)

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