Structure of PDB 7tj5 Chain B

Receptor sequence
>7tj5B (length=392) Species: 869211 (Spirochaeta thermophila DSM 6578) [Search protein sequence]
TYTLVWKVWILAVTLYYAIRIPLTLVFPSLFSPLLPLDILASLALIADIP
LDLAFESRLPDLLAALPLDLLVFALHLPSPLSLLSLVRLLKLISVQRSAT
RILSYRINPALLRLLSLVGFILLAAHGIACGWMSLQPPSENPAGTRYLSA
FYWTITTLTTIGYGDITPSTPTQTVYTIVIELLGAAMYGLVIGNIASLVS
KLDAAKLLHRERVERVTAFLSYKRISPELQRRIIEYFDYLWETRRGYEER
EVLKELPHPLRLAVAMEIHGDVIEKVPLFKGAGEEFIRDIILHLEPVIYG
PGEYIIRAGEMGSDVYFINRGSVEVLSADEKTRYAILSEGQFFGEMALIL
RAPRTATVRARAFCDLYRLDKETFDRILSRYPEIAAQIQELA
3D structure
PDB7tj5 Anionic lipids unlock the gates of select ion channels in the pacemaker family.
ChainB
Resolution2.41 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CMP B F366 G367 M369 R377 T378 A379 F343 G344 M346 R354 T355 A356
BS02 D21 B A166 Y170 A143 Y147
BS03 D21 B L34 S102 S157 L25 S79 S134
Gene Ontology
Molecular Function
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity
GO:0044877 protein-containing complex binding
Biological Process
GO:0034220 monoatomic ion transmembrane transport
GO:0098655 monoatomic cation transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7tj5, PDBe:7tj5, PDBj:7tj5
PDBsum7tj5
PubMed36352139
UniProtG0GA88

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