Structure of PDB 7t92 Chain B

Receptor sequence
>7t92B (length=360) Species: 573729 (Thermothelomyces thermophilus ATCC 42464) [Search protein sequence]
IDEHKPSLFELLSEQQLAALLPPTVRYLLTVLTQRYPRYLLRVLNSFDEL
YALAALVVERHYLRTRGGSFTEHFYGLKRERALVRDALRLRPADVWRNLL
VIVGVPYLKRKLDEAHEADAPRAMMGAAYNRPPLPGAPWRERVAFWWRCF
LRRVYPAVNAAYYLSILAFNLAYLFDNSKYHSPFLCLIGTRVRRMSAADY
RAIEALEERALVLPTSIFALKFLEWWYASDFAKQLSRKAAESLDLPPPVV
AGLPEEEKERRAIERAPVSASSLLPIYTVPPPENSDQCPICEGEITTAAA
CQTGIVYCYPCIHKWLTGTHPRQEKFMAERAGKWESGEGRCAVTGRRVLG
GTEGLRRIMV
3D structure
PDB7t92 A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel.
ChainB
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B C412 C415 C432 C435 C288 C291 C308 C311
BS02 LBN B Y82 L83 S303 F309 Y27 L28 S216 F222
Gene Ontology
Molecular Function
GO:0004842 ubiquitin-protein transferase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006513 protein monoubiquitination
GO:0015031 protein transport
GO:0016558 protein import into peroxisome matrix
GO:0016562 protein import into peroxisome matrix, receptor recycling
GO:0016567 protein ubiquitination
Cellular Component
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0016020 membrane
GO:1990429 peroxisomal importomer complex

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Molecular Function

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Cellular Component
External links
PDB RCSB:7t92, PDBe:7t92, PDBj:7t92
PDBsum7t92
PubMed35768507
UniProtG2Q5N0|PEX12_THET4 Peroxisome assembly protein 12 (Gene Name=PEX12)

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