Structure of PDB 7t7t Chain B

Receptor sequence

>7t7tB (length=432) Species: 55188 (Citrus unshiu)

GRDEMQMSEAKRAYRSAKEEGNRQEEARWANVIGDILKNRGEYVEALKWF
RIDYDLLPTCQSLGEVYLRLEHFKDALIYQKKHLELAKDASVEQQRACTQ
LGRTYYEMFDHYSIRNAKKYFKSAMKLAQTFLKEYIDAHNNIGMLQMELD
NLEEAKKLLIRGLEICNEEEVSEDDDGRSRLHHNLGNVYMELRMWDKSRE
HIEQDIIICKKIEHRQGEAKGYINLGELHYRVQKYDEAILCYQKALNLAQ
SMEDEDALASQIDQNIETVKKAIEVMDELKKEEQNLKKLTRNMIGTSQER
KSLLQQNASLDCLIEKSSMIFAWLKHCEYAKRKKRIASELCDKGKLSDSF
LVIGESYQKLRKFNKAIKWYTKSWEMYKSIEGQALAKVNMGNVLDSNGDW
ALDPSVQLSALENMHYSHMIRFDNIEEARRLQ

3D structure

• PDB: 7t7t The histone H3.1 variant regulates TONSOKU-mediated DNA repair during replication.
• Chain: B
• Resolution: 3.17 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	R29 N32 D36 Q72 S73 R109 Q113 R116 D166 M173 E177 R209 H212 N216 D234 K249 N253 E256 Y259 Q290 N294 T297 A301 M351 N424 N427 D430 Y467	R28 N31 D35 Q61 S62 R96 Q100 R103 D137 M144 E148 R180 H183 N187 D205 K220 N224 E227 Y230 Q261 N265 T268 A272 M319 N389 N392 D395 Y416

Gene Ontology

Biological Process

• GO:0006325 chromatin organization
• GO:0009933 meristem structural organization
• GO:0040029 epigenetic regulation of gene expression
• GO:0072423 response to DNA damage checkpoint signaling

Cellular Component

• GO:0005634 nucleus

External links

• PDB: RCSB:7t7t, PDBe:7t7t, PDBj:7t7t
• PDBsum: 7t7t
• PubMed: 35298257
• UniProt: A0A2H5Q1B8|TONSL_CITUN Protein TONSOKU (Gene Name=TSK)