Structure of PDB 7t7o Chain B

Receptor sequence
>7t7oB (length=438) Species: 4896 (Schizosaccharomyces pombe) [Search protein sequence]
MKFLNPPFPYSMTSDPESFGHECFTRRWGIILTGIEKDVSERLSKLASTS
KDSEVVAQGKPLLNDLEAFKSDIKNDRPLVPLEGEGQDIVEYNEELKQLD
NASWGNAPWLYSECYYYRRISLIFARYSEWKAYDPFFQQKDSTLKSSRAA
VEELAGRYCLLEEELNSIAKKGDSHIAYMVFVEMAQISLWGNATDLSLLT
NLSYEELQNLQGQKVVEESQKNILVNDFPTVWSKLKDVHNGRIDFVLDNA
GFELYVDLIFAAYLLKAGIAKEIVLHPKDFPWFVSDVLPYDIEYLLTNLD
TIFPTESVTKFATDLRSFSAKGQLRLRTDPFWTTAHYFGRMPDFAAGLLT
ELEKSDMIFFKGDLNYRKLTGDCLWPRTTPFGKTLGPIANAINACALRTC
KADVVVGLPDGLYEKIAKDLPHWERTGKYAVVEFCPKA
3D structure
PDB7t7o Fission yeast Duf89 and Duf8901 are cobalt/nickel-dependent phosphatase-pyrophosphatases that act via a covalent aspartyl-phosphate intermediate.
ChainB
Resolution2.16 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CO B X248 N249 D286 X248 N249 D286
Gene Ontology
Molecular Function
GO:0004427 inorganic diphosphate phosphatase activity
GO:0016787 hydrolase activity
GO:0016791 phosphatase activity
GO:0046872 metal ion binding
GO:0097023 fructose 6-phosphate aldolase activity
GO:0103026 fructose-1-phosphatase activity
Biological Process
GO:0006974 DNA damage response
GO:0030643 intracellular phosphate ion homeostasis
GO:1990748 cellular detoxification
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7t7o, PDBe:7t7o, PDBj:7t7o
PDBsum7t7o
PubMed35314193
UniProtQ9UT55|ART1A_SCHPO Damage-control phosphatase SPAC806.04c (Gene Name=SPAC806.04c)

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