Structure of PDB 7t6i Chain B

Receptor sequence
>7t6iB (length=182) Species: 9606 (Homo sapiens) [Search protein sequence]
ATPENYVYQGRQECYAFNGTQRFLERYIYNREEYARFDSDVGEFRAVTEL
GRPAAEYWNSQKDILEEKRAVPDRVCRHNYELDEAVTLQRRVQPKVNVSP
SHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVM
LEMTPQQGDVYICQVEHTSLDSPVTVEWKATG
3D structure
PDB7t6i Human T cells recognize HLA-DP-bound peptides in two orientations.
ChainB
Resolution2.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Q13 Y28 A55 W59 E68 K69 H79 N80 L83 D84 Q12 Y27 A54 W58 E67 K68 H78 N79 L82 D83
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7t6i, PDBe:7t6i, PDBj:7t6i
PDBsum7t6i
PubMed36442096
UniProtS6B6U4

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