Structure of PDB 7t5q Chain B

Receptor sequence
>7t5qB (length=372) Species: 9913 (Bos taurus) [Search protein sequence]
DSQGRKVVVCDNGTGFVKCGYAGSNFPEHIFPALVGRPIDLMVGDEASEL
RSMLEVNYPMENGIVRNWDDMKHLWDYTFGPEKLNIDTRNCKILLTEPPM
NPTKNREKIVEVMFETYQFSGVYVAIQAVLTLYAQGLLTGVVVDSGDGVT
HICPVYEGFSLPHLTRRLDIAGRDITRYLIKLLLLRGYAFNHSADFETVR
MIKEKLCYVGYNIEQEQKLALETTVLVESYTLPDGRIIKVGGERFEAPEA
LFQPHLINVEGVGVAELLFNTIQAADIDTRSEFYKHIVLSGGSTMYPGLP
SRLERELKQLYLERVLKGDVEKLSKFKIRIEDPPRRKHMVFLGGAVLADI
MKDKDNFWMTRQEYQEKGVRVL
3D structure
PDB7t5q Cryo-EM structure of an Arp2/3 complex mini-branch capped by capping protein (CapZ)
ChainB
Resolution3.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP B G14 T15 D161 G162 R214 E218 G306 Y310 G13 T14 D147 G148 R200 E204 G292 Y296
Gene Ontology
Molecular Function
GO:0003779 actin binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0051015 actin filament binding
Biological Process
GO:0010592 positive regulation of lamellipodium assembly
GO:0034314 Arp2/3 complex-mediated actin nucleation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:1905168 positive regulation of double-strand break repair via homologous recombination
GO:2001032 regulation of double-strand break repair via nonhomologous end joining
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005885 Arp2/3 protein complex
GO:0005938 cell cortex
GO:0035861 site of double-strand break
GO:0042995 cell projection

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7t5q, PDBe:7t5q, PDBj:7t5q
PDBsum7t5q
PubMed
UniProtA7MB62|ARP2_BOVIN Actin-related protein 2 (Gene Name=ACTR2)

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