Structure of PDB 7t3i Chain B

Receptor sequence

>7t3iB (length=578) Species: 209285 (Thermochaetoides thermophila)

RTPPTKVSILDIAGVDDTLQRLLKEVWFPLRGGEACEKMGYRYDNGVLLH
GPSGCGKTTLAHAIAGSIGVAFIPVSAPSVIGGTSGESEKNIRDVFDEAI
RLAPCLIFLDEIDAIAGRRESANKGMESRIVAEIMNGMDRIRQNTPLGKN
VVVLAATNRPEFLDPAIRRRFSVEIDMGMPSERAREQILRSLTRDLSLAD
DINFKELAKMTPGYVGSDLQYVVKAAVSESFQANIDSLLAQARAKHPADH
LANVSQPQRDWLLLEAHRDEEVSWPSTKITMEQFRKAVSLVQPASKREGF
STIPDTTWSHVGALEDVRKKLEMSIIGPIKNPELFTRVGIKPAAGILLWG
PPGCGKTLVAKAVANESKANFISIKGPELLNKYVGESERAVRQLFSRAKS
SAPCILFFDQMDALVPRRDDSLSDASARVVNTLLTELDGVGDRSGIYVIG
ATNRPDMIDEAIRRPGRLGTSIYVGLPSAEDRVKILKTLYRNTVQGTTDA
DLEKVALDLRCTGFSGADLGNLMQAAAQACLERVYTQRQQKRKEGEEEIE
PVITMEDWEKALNEVKPSVKDPEKYMHS

3D structure

• PDB: 7t3i Communication network within the essential AAA-ATPase Rix7 drives ribosome assembly.
• Chain: B
• Resolution: 4.3 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	T276 S277 K574	T84 S85 K382
BS02	ATP	B	R656 R659	R464 R467
BS03	ATP	B	R361 R362	R169 R170
BS04	ATP	B	G246 C247 G248 K249 T250 T251 I380 L384 G408	G54 C55 G56 K57 T58 T59 I188 L192 G216
BS05	ATP	B	V503 G504 G545 G547 K548 T549 L550 I677 G733 A734	V311 G312 G353 G355 K356 T357 L358 I485 G516 A517

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0005524 ATP binding
• GO:0016887 ATP hydrolysis activity
• GO:1990275 preribosome binding

Biological Process

• GO:0042254 ribosome biogenesis

Cellular Component

• GO:0005634 nucleus

External links

• PDB: RCSB:7t3i, PDBe:7t3i, PDBj:7t3i
• PDBsum: 7t3i
• PubMed: 36090660
• UniProt: G0RZG1