Structure of PDB 7t2a Chain B

Receptor sequence
>7t2aB (length=177) Species: 9606 (Homo sapiens) [Search protein sequence]
TPENYLFQGRQECYAFNGTQRFLERYIYNREEFARFDSDVGEFRAVTELG
RPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMTLQRRVQPRVNVSPS
NLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRNGDWTFQILVMLE
MTPQQGDVYTCQVEHTSLDSPVTVEWK
3D structure
PDB7t2a CD4 + T cell-mediated recognition of a conserved cholesterol-dependent cytolysin epitope generates broad antibacterial immunity.
ChainB
Resolution3.04 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B G11 R12 Q13 E28 Y30 Y60 W61 I67 E70 K71 V74 R77 M78 H81 N82 L85 G9 R10 Q11 E24 Y26 Y56 W57 I63 E66 K67 V70 R73 M74 H77 N78 L81
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7t2a, PDBe:7t2a, PDBj:7t2a
PDBsum7t2a
PubMed37100059
UniProtP04440|DPB1_HUMAN HLA class II histocompatibility antigen, DP beta 1 chain (Gene Name=HLA-DPB1)

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