Structure of PDB 7t1u Chain B

Receptor sequence
>7t1uB (length=107) Species: 9606 (Homo sapiens) [Search protein sequence]
GGAPWQAEEWYFGKITRRESERLLLNAENPRGTFLVREGQSQPDYVLSVS
DFDNAKGLNVKHYIIRKLDSGFYITSRTQFNSLQQLVAYYSKHADGLCHR
LTTVCPT
3D structure
PDB7t1u Engineered SH2 Domains for Targeted Phosphoproteomics.
ChainB
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R158 R178 G180 S182 Q183 K202 H203 Y204 I205 I216 G238 R17 R37 G39 S41 Q42 K61 H62 Y63 I64 I74 G96
BS02 ZN B D192 D194 D51 D53
External links
PDB RCSB:7t1u, PDBe:7t1u, PDBj:7t1u
PDBsum7t1u
PubMed35613471
UniProtP12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)

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