Structure of PDB 7t1l Chain B

Receptor sequence
>7t1lB (length=100) Species: 9606 (Homo sapiens) [Search protein sequence]
GKPLHEQLWYHGAIPRAEVAELLVHSGDFLVRESETVKGAYALSVLWDGL
PRHFLIQSLDNLYRLEGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHRAVP
3D structure
PDB7t1l Engineered SH2 Domains for Targeted Phosphoproteomics.
ChainB
Resolution1.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B T36 V37 K38 Q57 S58 T36 V37 K38 Q57 S58
BS02 peptide B R16 R32 S34 E35 T36 R52 H53 F54 L55 Q57 R16 R32 S34 E35 T36 R52 H53 F54 L55 Q57
External links
PDB RCSB:7t1l, PDBe:7t1l, PDBj:7t1l
PDBsum7t1l
PubMed35613471
UniProtP07332|FES_HUMAN Tyrosine-protein kinase Fes/Fps (Gene Name=FES)

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