Structure of PDB 7stm Chain B

Receptor sequence
>7stmB (length=801) Species: 5476 (Candida albicans) [Search protein sequence]
QAFIPHVYDEEDNDEQEYDQRIQYNQFQGDHFDLAATRATGLNGHLVLDC
PVADELLSKFPDYNPAEKSGGLSREFAFMRYTAVTCGPSNFYRDAYILRP
VHYPIPRQTELMIVITMYNEDDILLGRTLKGVFKNIKYLESKARSSTWGK
DSWKKIVVCIVSDGRTKINERAQALLAGLGVYQEGLAKSRVDDKKVQAHM
FEYTTRVGISKVTDDVVKLTTEKVVPVQMLFCLKETNAKKINSHRWCFQA
IGQVLDPKIVVLLDCGTQPSGRSLYELWKEFDRDHRVAGACGEITTSLKK
RQMITNPLVYGQNFEYKISNILDKPTESSFGFISVLPGAFSAYRFIALQN
DINGVGPLEKYFKGEFLHSSGELDPNDDEFQMKHLMLKEEAGIFTSNMYL
AEDRILCFELVAKRGCNWLLRYCKSARAETDVPEGLAEFILQRRRWLNGS
FFAAIYSLVHFYKVWTSSHSFGRKIFLHIEFFYQLINLIVSWFSIGSYFL
VFRILTTSLGDKALGFAPGKILSVIFLWLYLASIVTTFVLSFGNKPKGTE
KFYVTIVIFFAILMAYMIFAAIFMAVHSIQDIYRSGTRITVSLFFQNSEF
RDLVVATSSTYALYFLASFLYFEPWHMFTSFVQYILLSPSYVNVLNIYAF
CNIDDISWGTKGEVGGKSLGEAKLREDGTFDVSVPISKEQINQSYLDQLE
KIRDPAPPEEKVLVTNTEDYYAFIRSMTVLVWMFTNFVVIALVLETGGFN
QFVEATDLANLKSNRAAVFLTVILWTVAFMALFRFIGCIYYLITRLGREI
K
3D structure
PDB7stm Structural basis for inhibition and regulation of a chitin synthase from Candida albicans.
ChainB
Resolution3.02 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.16: chitin synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 UD1 B T317 Y319 E321 D364 D465 Q643 R646 T116 Y118 E120 D163 D264 Q442 R445
Gene Ontology
Molecular Function
GO:0004100 chitin synthase activity
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
Biological Process
GO:0006031 chitin biosynthetic process
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane
GO:0030428 cell septum
GO:0071944 cell periphery

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7stm, PDBe:7stm, PDBj:7stm
PDBsum7stm
PubMed35788183
UniProtP30572|CHS2_CANAX Chitin synthase 2 (Gene Name=CHS2)

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