Structure of PDB 7stb Chain B

Receptor sequence
>7stbB (length=315) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
LQLPWVEKYRPQVLSDIVGNKETIDRLQQIAKDGNMPHMIISGMPGIGKT
TSVHCLAHELLGRSYADGVLELNASDDRGIDVVRNQIKHFAQKKLHLPPG
KHKIVILDEADSMTAGAQQALRRTMELYSNSTRFAFACNQSNKIIEPLQS
RCAILRYSKLSDEDVLKRLLQIIKLEDVKYTNDGLEAIIFTAEGDMRQAI
NNLQSTVAGHGLVNADNVFKIVDSPHPLIVKKMLLASNLEDSIQILRTDL
WKKGYSSIDIVTTSFRVTKNLAQVKESVRLEMIKEIGLTHMRILEGVGTY
LQLASMLAKIHKLNN
3D structure
PDB7stb Mechanisms of loading and release of the 9-1-1 checkpoint clamp.
ChainB
Resolution2.72 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B G85 I86 R90 G79 I80 R84
BS02 MG B T56 D114 T50 D108
BS03 AGS B V12 R16 P17 I23 V24 P51 G52 I53 G54 K55 T56 T57 M202 R203 V6 R10 P11 I17 V18 P45 G46 I47 G48 K49 T50 T51 M196 R197
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003689 DNA clamp loader activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0000077 DNA damage checkpoint signaling
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006271 DNA strand elongation involved in DNA replication
GO:0006272 leading strand elongation
GO:0006281 DNA repair
GO:0007062 sister chromatid cohesion
GO:0007064 mitotic sister chromatid cohesion
GO:0090618 DNA clamp unloading
Cellular Component
GO:0005634 nucleus
GO:0005663 DNA replication factor C complex
GO:0005829 cytosol
GO:0031389 Rad17 RFC-like complex
GO:0031390 Ctf18 RFC-like complex
GO:0031391 Elg1 RFC-like complex

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7stb, PDBe:7stb, PDBj:7stb
PDBsum7stb
PubMed35314831
UniProtP40339|RFC4_YEAST Replication factor C subunit 4 (Gene Name=RFC4)

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