Structure of PDB 7sn6 Chain B

Receptor sequence
>7sn6B (length=105) Species: 9606 (Homo sapiens) [Search protein sequence]
PLGSTEVLCLMNMVLPEELLDDEEYEEIVEDVRDECSKYGLVKSIEIPRP
VDGVEVPGCGKIFVEFTSVFDCQKAMQGLTGRKFANRVVVTKYCDPDSYH
RRDFW
3D structure
PDB7sn6 A UHM-ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing.
ChainB
Resolution1.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B M383 E394 E397 D401 E405 K408 R452 K453 F454 A455 M13 E24 E27 D31 E35 K38 R82 K83 F84 A85
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:7sn6, PDBe:7sn6, PDBj:7sn6
PDBsum7sn6
PubMed35780835
UniProtP26368|U2AF2_HUMAN Splicing factor U2AF 65 kDa subunit (Gene Name=U2AF2)

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