Structure of PDB 7skq Chain B

Receptor sequence
>7skqB (length=304) Species: 347537 (Bat SARS CoV Rf1/2004) [Search protein sequence]
IKVFTTVDNTNLHTQLVDMSMTYGQHFGPTYLDGADVTKVKPHVNHEGKT
FFVLPSEAFEYYHTLDESFLGRYMSALNHTKKWKFPQVGGLTSIKWADNN
CYLSSVLLALQQIEVKFNAPALQEAYYRARAGDAANFCALILAYSNKTVG
ELGDVRETMTHLLQHANLESAKRVLNLVCKHCGQKTTTLMGVEAVMYMGT
LSYDELKAGVSIPCVCGRDATQYLVQQESSFVMMSAPPAEYKLQQGTFLC
ANEYTGNYQCGHYTHITAKETLYRIDGAHLTKMSEYKGPVTDVFYKETSY
TTTI
3D structure
PDB7skq Exploring Noncovalent Protease Inhibitors for the Treatment of Severe Acute Respiratory Syndrome and Severe Acute Respiratory Syndrome-Like Coronaviruses.
ChainB
Resolution3.16 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.19.12: ubiquitinyl hydrolase 1.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 TTT B L163 D165 P249 Y265 Y269 Q270 Y274 T302 L152 D154 P238 Y254 Y258 Q259 Y263 T291
BS02 ZN B C193 C225 C182 C214
BS03 ZN B H90 D109 H79 D98
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function

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Biological Process
External links
PDB RCSB:7skq, PDBe:7skq, PDBj:7skq
PDBsum7skq
PubMed35199517
UniProtQ0QDZ2

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