Structure of PDB 7sg2 Chain B

Receptor sequence
>7sg2B (length=175) Species: 9606 (Homo sapiens) [Search protein sequence]
SPEDFVYQFKGMCYFTNGTERVRLVSRSIYNREEIVRFDSDVGEFRAVTL
LGLPAAEYWNSQKDILERKRAAVDRVCRHNYQLELRTTLQRRVEPTVTIS
PSNLLVCSVTDFYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVM
LEMDVYTCHVEHPSLQSPITVEWRA
3D structure
PDB7sg2 Structural basis of T cell receptor specificity and cross-reactivity of two HLA-DQ2.5-restricted gluten epitopes in celiac disease.
ChainB
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B Y9 F11 G13 L26 S30 A57 W61 I67 R77 V78 N82 Y7 F9 G11 L24 S28 A55 W59 I65 R75 V76 N80
BS02 CA B T185 E187 T170 E172
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:7sg2, PDBe:7sg2, PDBj:7sg2
PDBsum7sg2
PubMed35065967
UniProtQ5Y7D3

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