Structure of PDB 7sfo Chain B

Receptor sequence
>7sfoB (length=229) Species: 9606 (Homo sapiens) [Search protein sequence]
ALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVH
MINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAP
NLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS
NKGMEHLYSMKCKNVVPLSDLLLEMLDAH
3D structure
PDB7sfo Estrogen Receptor Alpha
ChainB
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B I358 K362 L372 V376 E380 L539 E542 M543 I52 K56 L66 V70 E74 L221 E224 M225
BS02 98L B E353 W383 L384 L391 F404 M421 I424 F425 L428 H524 E47 W77 L78 L85 F98 M115 I118 F119 L122 H206
External links
PDB RCSB:7sfo, PDBe:7sfo, PDBj:7sfo
PDBsum7sfo
PubMed
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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