Structure of PDB 7s7c Chain B

Receptor sequence
>7s7cB (length=330) Species: 9606 (Homo sapiens) [Search protein sequence]
ENQELKRKLNILTRPSGILVNDTKLDGPILQILFMNNAISKQYHQEIEEF
VSNLVKRFEEQQKNDVEKTSFNLLPQPSSIVLEEDHKVEESCAIKNNKEA
FSVVGSVLYFTNFCLDKLGQPLLNENPQLSEGWEIPKYHQVFSHIVSLEG
QHCFNCGSEEHQMKDCPMPQQRYHAEEVEERFGRFKPGVISEELQDALGV
TDKSLPPFIYRMRQLGYPPGWLKEAELENSGLALYDGKSVTYDLSKLVNY
PGFNISTPRGIPDEWRIFGSIPMQACQQKDVFANYLPIPDMSKFATGITP
FEFENMAESTGMYLRIRSLLKNSPRNQQKN
3D structure
PDB7s7c Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex.
ChainB
Resolution3.62 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B F230 C232 G233 F154 C156 G157
BS02 ZN B C229 C232 S234 H237 C242 C153 C156 S158 H161 C166
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:7s7c, PDBe:7s7c, PDBj:7s7c
PDBsum7s7c
PubMed35688134
UniProtQ6NZY4|ZCHC8_HUMAN Zinc finger CCHC domain-containing protein 8 (Gene Name=ZCCHC8)

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