Structure of PDB 7s1o Chain B

Receptor sequence
>7s1oB (length=302) Species: 9606 (Homo sapiens) [Search protein sequence]
LSATILTDHQYLERTPLCAILKQKAPQQYRIRAKLRSYKPRRLFQSVKLH
CPKCHLLQEVPHEGDLDIIFQDGATKTPDVKLQNTSLYDSKIWTTKNQKG
RKVAVHFVKNNGILPLSNECLLLIEGGTLSEICKLSNKFNSVIPVRSGHE
DLELLDLSAPFLIQGTIHHYGCKQCSSLRSIQNLNSLVDKTSWIPSSVAE
ALGIVPLQYVFVMTFTLDDGTGVLEAYLMDSDKFFQIPASEVLMDDDLQK
SVDMIMDMFCPPGIKIDAYPWLECFIKSYNVTNGTDNQICYQIFDTTVAE
DV
3D structure
PDB7s1o POT1-TPP1 binding stabilizes POT1, promoting efficient telomere maintenance.
ChainB
Resolution2.55 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C382 C503 C506 C51 C172 C175
Gene Ontology
Molecular Function
GO:0043047 single-stranded telomeric DNA binding
Biological Process
GO:0000723 telomere maintenance

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Molecular Function
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Biological Process
External links
PDB RCSB:7s1o, PDBe:7s1o, PDBj:7s1o
PDBsum7s1o
PubMed35140887
UniProtQ9NUX5|POTE1_HUMAN Protection of telomeres protein 1 (Gene Name=POT1)

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