Structure of PDB 7ru9 Chain B

Receptor sequence
>7ru9B (length=306) Species: 7955 (Danio rerio) [Search protein sequence]
EPLEPTLKNIIEQKSLKWIFVGGKGGVGKTTCSCSLAVQLAAVRESVLII
STNPAHNISDAFDQKFSKVPTKVKGYDNLFAMEIDPSLGVAELPDEFFEE
DNMLSMGKKMMQEAMSAFPGIDEAMSYAEVMRLVKGMNFSVVVFDTAPTG
HTLRLLNFPTIVERGLGRLMQIKNQADQLASKLEETLPVIRSVSEQFKDP
EQTTFICVCIAEFLSLYETERLIQELAKCRIDTHNIIVNQLVFPDNERPC
KMCEARHKIQSKYLDQMEDLYEDFHIVKLPLLPHEVRGADKVNTFSKQLL
EPYSPP
3D structure
PDB7ru9 Structural insights into metazoan pretargeting GET complexes.
ChainB
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ATP B K39 G40 E245 K24 G25 E212
BS02 ATP B G43 K44 T45 T46 N272 L314 L315 G28 K29 T30 T31 N239 L281 L282
BS03 MG B T45 D160 T30 D145
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0046872 metal ion binding
Biological Process
GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane
GO:0007416 synapse assembly
GO:0045048 protein insertion into ER membrane
GO:0071816 tail-anchored membrane protein insertion into ER membrane
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0043529 GET complex

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Biological Process

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Cellular Component
External links
PDB RCSB:7ru9, PDBe:7ru9, PDBj:7ru9
PDBsum7ru9
PubMed34887561
UniProtQ6IQE5|GET3_DANRE ATPase GET3 (Gene Name=get3)

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