Structure of PDB 7rhk Chain B

Receptor sequence
>7rhkB (length=418) Species: 9606 (Homo sapiens) [Search protein sequence]
PQSIDPLTNLMYVLWLFFVVMAWNWNCWLIPVRWAFPYQTPDNIHHWLLM
DYLCDLIYFLDITVFQTRLQFVRGGDIITDKKDMRNNYLKSRRFKMDLLS
LLPLVNPLLRLPRCLKYMAFFEFNSRLESILSKAYVYRVIRTTAYLLYSL
HLNSCLYYWASAYNSYIRCYYFAVKTLITIGGLPDPKTLFEIVFQLLNYF
TGVFAFSVMIGQMRDVVGAATAGQTYYRSCMDSTVKYMNFYKIPKSVQNR
VKTWYEYTWHSQGMLDESELMVQLPDKMRLDLAIDVNYNIVSKVALFQGC
DRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVLGGPDGK
SVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEIL
VHYPESQKLLRKKARRML
3D structure
PDB7rhk Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
ChainB
Resolution3.27 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 PCG B L1019 F1028 R1042 T1043 L353 F362 R376 T377
BS02 5H0 B I844 F872 I178 F206
Gene Ontology
Molecular Function
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity

View graph for
Molecular Function
External links
PDB RCSB:7rhk, PDBe:7rhk, PDBj:7rhk
PDBsum7rhk
PubMed34699778
UniProtQ14028|CNGB1_HUMAN Cyclic nucleotide-gated channel beta-1 (Gene Name=CNGB1)

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