Structure of PDB 7rhg Chain B

Receptor sequence
>7rhgB (length=432) Species: 9606 (Homo sapiens) [Search protein sequence]
PQSIDPLTNLMYVLWLFFVVMAWNWNCWLIPVRWAFPYQTPDNIHHWLLM
DYLCDLIYFLDITVFQTRLQFVRGGDIITDKKDMRNNYLKSRRFKMDLLS
LLPLVNPLLRLPRCLKYMAFFEFNSRLESILSKAYVYRVIRTTAYLLYSL
HLNSCLYYWASAYQGLGSTHWVYDGVGNSYIRCYYFAVKTLITIGGLPDP
KTLFEIVFQLLNYFTGVFAFSVMIGQMRDVVGAATAGQTYYRSCMDSTVK
YMNFYKIPKSVQNRVKTWYEYTWHSQGMLDESELMVQLPDKMRLDLAIDV
NYNIVSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYII
QAGQVQVLGGPDGKSVLVTLKAGSVFGEISLLAVGGGNRRTANVVAHGFT
NLFILDKKDLNEILVHYPESQKLLRKKARRML
3D structure
PDB7rhg Structural mechanisms of assembly, permeation, gating, and pharmacology of native human rod CNG channel.
ChainB
Resolution2.88 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 CMP B V1009 V1020 R1042 V357 V368 R390
Gene Ontology
Molecular Function
GO:0005221 intracellularly cyclic nucleotide-activated monoatomic cation channel activity

View graph for
Molecular Function
External links
PDB RCSB:7rhg, PDBe:7rhg, PDBj:7rhg
PDBsum7rhg
PubMed34699778
UniProtQ14028|CNGB1_HUMAN Cyclic nucleotide-gated channel beta-1 (Gene Name=CNGB1)

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