Structure of PDB 7qkc Chain B

Receptor sequence
>7qkcB (length=216) Species: 9606 (Homo sapiens) [Search protein sequence]
APRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSE
QNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKY
NPKYSVANDAGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGI
YFEPDCSSEDMDHGVLVVGYGFESNNKYWLVKNSWGEEWGMGGYVKMAKD
RRNHCGIASAASYPTV
3D structure
PDB7qkc Sulfonated Calpeptin is a promising drug candidate against SARS-CoV-2 infections
ChainB
Resolution1.69 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.15: cathepsin L.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RN2 B G23 C25 E63 G67 G68 L69 M70 M161 D162 H163 G23 C25 E63 G67 G68 L69 M70 M161 D162 H163
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7qkc, PDBe:7qkc, PDBj:7qkc
PDBsum7qkc
PubMed37853179
UniProtP07711|CATL1_HUMAN Procathepsin L (Gene Name=CTSL)

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