Structure of PDB 7qhp Chain B

Receptor sequence
>7qhpB (length=184) Species: 10090 (Mus musculus) [Search protein sequence]
RHFVHQFKGECYFTNGTQRIRLVTRYIYNREEYLRFDSDVGEYRAVTELG
RHSAEYYNKQYLERTRAELDTACRHNYEETEVPTSLRRLEQPNVAISLSR
TEALNHHNTLVCSVTDFYPAKIKVRWFRNGQEETVGVSSTQLIRNGDWTF
QVLVMLEMTPHQEVYTCHVEHPSLKSPITVEWRA
3D structure
PDB7qhp Structural plasticity in I-A g7 links autoreactivity to hybrid insulin peptides in type I diabetes.
ChainB
Resolution1.82 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B F11 G13 L26 Y30 Y60 Y61 Y65 R68 E72 H79 N80 E83 T84 F7 G9 L22 Y26 Y56 Y57 Y61 R64 E68 H75 N76 E79 T80
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7qhp, PDBe:7qhp, PDBj:7qhp
PDBsum7qhp
PubMed35967292
UniProtQ31135

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