Structure of PDB 7qgw Chain B

Receptor sequence
>7qgwB (length=221) Species: 9606 (Homo sapiens) [Search protein sequence]
LPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSE
QNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKY
RPENSVAQDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSG
IYFEPDCSSKNLDHGVLVVGYGFEGANSQNSKYWLVKNSWGPEWGSNGYV
KIAKDKNNHCGIATAASYPNV
3D structure
PDB7qgw Sulfonated Calpeptin is a promising drug candidate against SARS-CoV-2 infections
ChainB
Resolution1.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.22.43: cathepsin V.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RN2 B G245 C247 G283 Q285 N288 G289 G290 F291 M292 G23 C25 G61 Q63 N66 G67 G68 F69 M70
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:7qgw, PDBe:7qgw, PDBj:7qgw
PDBsum7qgw
PubMed37853179
UniProtO60911|CATL2_HUMAN Cathepsin L2 (Gene Name=CTSV)

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