Structure of PDB 7qde Chain B

Receptor sequence
>7qdeB (length=169) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
MHHRQEGELSNTRLFVRPFPLDVQESELNEIFGPFGPMKEVKILNGFAFV
EFEEAESAAKAIEEVHGKSFANQPLEVVYSKLPAKRYRITMKNLPEGCSW
QDLKDLARENSLETTFSSVNTRDFDGTGALEFPSEEILVEALERLNNIEF
RGSVITVERDDNPPPIRRS
3D structure
PDB7qde NMR structure of Npl3 RRM12 bound to the AUCCAGUGGAA RNA
ChainB
ResolutionN/A
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 rna B M114 R126 F128 R130 K155 L157 F160 F162 Y192 S193 K194 L195 P196 R199 S212 W213 Q214 D215 K217 D218 F229 S230 E244 P278 I279 S282 M1 R13 F15 R17 K42 L44 F47 F49 Y79 S80 K81 L82 P83 R86 S99 W100 Q101 D102 K104 D105 F116 S117 E131 P165 I166 S169
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:7qde, PDBe:7qde, PDBj:7qde
PDBsum7qde
PubMed37935663
UniProtQ01560|NOP3_YEAST Serine/arginine (SR)-type shuttling mRNA binding protein NPL3 (Gene Name=NPL3)

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