Structure of PDB 7psx Chain B
Receptor sequence
>7psxB (length=60) Species:
9606
(Homo sapiens) [
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KKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNR
RVKEKKVLAK
3D structure
PDB
7psx
Structure of HOXB13 bound to hydroxymethylated DNA
Chain
B
Resolution
2.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
dna
B
S224 G226
S7 G9
BS02
dna
B
K218 R220 Y223 R258 Q259 I262 N266 K270
K1 R3 Y6 R41 Q42 I45 N49 K53
BS03
dna
B
R220 P222 F240 K243 R246 Q265 R268 K272
R3 P5 F23 K26 R29 Q48 R51 K55
Gene Ontology
Molecular Function
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677
DNA binding
Biological Process
GO:0006355
regulation of DNA-templated transcription
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:7psx
,
PDBe:7psx
,
PDBj:7psx
PDBsum
7psx
PubMed
UniProt
Q92826
|HXB13_HUMAN Homeobox protein Hox-B13 (Gene Name=HOXB13)
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