Structure of PDB 7prt Chain B

Receptor sequence
>7prtB (length=74) Species: 9606 (Homo sapiens) [Search protein sequence]
QDVVDLDFFTQEPLHLVSPSFLSVTIDANLATDPRFLILLGSPKLRTLAR
GLSPAYLRFGGTKTDFLIFDPKKE
3D structure
PDB7prt Mechanism-based heparanase inhibitors reduce cancer metastasis in vivo.
ChainB
Resolution1.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.166: heparanase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 8I4 B D27 G61 T62 D27 G61 T62
External links
PDB RCSB:7prt, PDBe:7prt, PDBj:7prt
PDBsum7prt
PubMed35881786
UniProtQ9Y251|HPSE_HUMAN Heparanase (Gene Name=HPSE)

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