Structure of PDB 7pdf Chain B

Receptor sequence
>7pdfB (length=341) Species: 9913 (Bos taurus) [Search protein sequence]
KQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVKATKVQDIKNNL
KEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEH
AKALWEDEGVRACYERSNEYQLIDCAQYFLDKIDVIKQDDYVPSDQDLLR
CRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVA
SSSYNMVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAE
KVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRVTRAKYFIRDEFLRIS
TASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQ
3D structure
PDB7pdf Structural basis of adenylyl cyclase 9 activation.
ChainB
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GSP B G49 E50 G52 K53 S54 T55 D173 C174 R199 R201 T204 N292 K293 D295 L296 C365 A366 V367 G22 E23 G25 K26 S27 T28 D124 C125 R150 R152 T155 N243 K244 D246 L247 C316 A317 V318
BS02 MG B S54 T204 S27 T155
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0019001 guanyl nucleotide binding
GO:0031683 G-protein beta/gamma-subunit complex binding
Biological Process
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway

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Molecular Function
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Biological Process
External links
PDB RCSB:7pdf, PDBe:7pdf, PDBj:7pdf
PDBsum7pdf
PubMed35210418
UniProtP04896|GNAS2_BOVIN Guanine nucleotide-binding protein G(s) subunit alpha isoforms short (Gene Name=GNAS)

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