Structure of PDB 7p92 Chain B

Receptor sequence

>7p92B (length=612) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]

MFKNAKEFVQYANKLKTLREKKLNGVSIYVCVGTGCTAKGALKVYSAFEE
ELKKRNLKVTLNRTGCCGRCSSGPLVKIMPYRFFYSNVAPEDVPEIVDRT
VLKGEPIERLFLTDPLTGEKVPRIEDTTLFKNQDFYIMEAIGESECDSIE
DYIARSGYESLVKALTSMTPEEIIETVKASGLRGRGGGGFPTGLKWEFTR
KAQGDIKFVVCNGDEGDPGAFMNRTLLERDPHLVLEGMIIAGYAVGAQKG
YAYIRAEYPFAVKMFKKAIEDARKLGLLGENILGTGFSFDLEVKEGAGAF
VCGEETALLASIEGKRGMPRPKPPFPAQSGLWGKPTLINNVETYANIPRI
LRDGVENYRKRGTENSPGTKMFSVAGPLKATGIIEVEFGTTLRDIIYNIC
GGFVEGEEFKAVQIGGPSGACLSEDFIDMPLDYDTLKKADAMVGSGGIVV
ITKKTCMVEVARFFLDFTKRESCGKCVPCREGTMQAYNILEKFTHGKATY
EDLKTLEHLSKTIKTASLCGLGKTAPNPILSTLKLFREEYIAHIEGECPS
GMCTAFKKYVINPDICKGCGLCARSCPQNAITGERGKPYTIDQEKCVKCG
LCASKCPFKAIE

3D structure

PDB

7p92 Structural insight on the mechanism of an electron-bifurcating [FeFe] hydrogenase.

Chain

Resolution

2.7 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

1.12.1.4: hydrogenase (NAD(+), ferredoxin).

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	SF4	B	C588 C608 C611 G612 L613 C614	C576 C596 C599 G600 L601 C602
BS02	SF4	B	C578 G580 C581 G582 L583 C584 K617 C618	C566 G568 C569 G570 L571 C572 K605 C606
BS03	SF4	B	P331 S484 C485 G486 K487 C488 C491 L530 C531 L533 G534	P319 S472 C473 G474 K475 C476 C479 L518 C519 L521 G522
BS04	FMN	B	G196 G198 K207 D226 E227 G228 F312 G315 N351 N352 T355 G532 L533	G184 G186 K195 D214 E215 G216 F300 G303 N339 N340 T343 G520 L521
BS05	FES	B	C31 G33 T34 C36 C78 C79 G80 R81 C82	C31 G33 T34 C36 C66 C67 G68 R69 C70
BS06	ZN	B	C468 H555 C560 C565	C456 H543 C548 C553

Gene Ontology

	Molecular Function
GO:0008137	NADH dehydrogenase (ubiquinone) activity
GO:0010181	FMN binding
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding
GO:0051539	4 iron, 4 sulfur cluster binding

	Biological Process
GO:1902600	proton transmembrane transport

	Cellular Component
GO:0005737	cytoplasm

View graph for
Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:7p92, PDBe:7p92, PDBj:7p92
PDBsum	7p92
PubMed	36018003
UniProt	O52682\|HYDB_THEMA Bifurcating [FeFe] hydrogenase beta subunit (Gene Name=hydB)

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