Structure of PDB 7p91 Chain B

Receptor sequence

>7p91B (length=613) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence]

MFKNAKEFVQYANKLKTLREKKLNGVSIYVCVGTGCTAKGALKVYSAFEE
ELKKRNLLKVTLNRTGCCGRCSSGPLVKIMPYRFFYSNVAPEDVPEIVDR
TVLKGEPIERLFLTDPLTGEKVPRIEDTTLFKNQDFYIMEAIGESECDSI
EDYIARSGYESLVKALTSMTPEEIIETVKASGLRGRGGGGFPTGLKWEFT
RKAQGDIKFVVCNGDEGDPGAFMNRTLLERDPHLVLEGMIIAGYAVGAQK
GYAYIRAEYPFAVKMFKKAIEDARKLGLLGENILGTGFSFDLEVKEGAGA
FVCGEETALLASIEGKRGMPRPKPPFPAQSGLWGKPTLINNVETYANIPR
ILRDGVENYRKRGTENSPGTKMFSVAGPLKATGIIEVEFGTTLRDIIYNI
CGGFVEGEEFKAVQIGGPSGACLSEDFIDMPLDYDTLKKADAMVGSGGIV
VITKKTCMVEVARFFLDFTKRESCGKCVPCREGTMQAYNILEKFTHGKAT
YEDLKTLEHLSKTIKTASLCGLGKTAPNPILSTLKLFREEYIAHIEGECP
SGMCTAFKKYVINPDICKGCGLCARSCPQNAITGERGKPYTIDQEKCVKC
GLCASKCPFKAIE

3D structure

PDB

7p91 Structural insight on the mechanism of an electron-bifurcating [FeFe] hydrogenase.

Chain

Resolution

2.8 Å

3D
structure

[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Enzyme Commision number

1.12.1.4: hydrogenase (NAD(+), ferredoxin).

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	SF4	B	Y571 C588 I603 C608 V609 C611 G612 C614	Y560 C577 I592 C597 V598 C600 G601 C603
BS02	SF4	B	C578 C581 G582 C584 Y601 C618	C567 C570 G571 C573 Y590 C607
BS03	SF4	B	P331 S484 C485 G486 K487 C488 C491 L530 C531 L533 G534	P320 S473 C474 G475 K476 C477 C480 L519 C520 L522 G523
BS04	FMN	B	G196 G198 K207 N224 D226 E227 G228 G315 E316 E317 N351 N352 G532 L533	G185 G187 K196 N213 D215 E216 G217 G304 E305 E306 N340 N341 G521 L522
BS05	FES	B	C31 G33 T34 C36 C78 C79 G80 R81 C82	C31 G33 T34 C36 C67 C68 G69 R70 C71
BS06	ZN	B	C468 H555 C560 C565	C457 H544 C549 C554

Gene Ontology

	Molecular Function
GO:0008137	NADH dehydrogenase (ubiquinone) activity
GO:0010181	FMN binding
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding
GO:0051539	4 iron, 4 sulfur cluster binding

	Biological Process
GO:1902600	proton transmembrane transport

	Cellular Component
GO:0005737	cytoplasm

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:7p91, PDBe:7p91, PDBj:7p91
PDBsum	7p91
PubMed	36018003
UniProt	O52682\|HYDB_THEMA Bifurcating [FeFe] hydrogenase beta subunit (Gene Name=hydB)

[Back to BioLiP]