Structure of PDB 7p7g Chain B

Receptor sequence
>7p7gB (length=283) Species: 9606 (Homo sapiens) [Search protein sequence]
NRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIY
KMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVL
LLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKY
RDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYVLMYF
NLGSLPWQGLATKRQKYERISEKKMSTPIEVLCKGYPSEFATYLNFCRSL
RFDDKPDYSYLRQLFRNLFHRQGFDYVFDWNML
3D structure
PDB7p7g Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes.
ChainB
Resolution1.7 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
2.7.11.26: [tau protein] kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP B I15 G18 I23 A36 K38 M82 L85 D132 L135 I148 D149 I9 G12 I17 A30 K32 M76 L79 D126 L129 I142 D143
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7p7g, PDBe:7p7g, PDBj:7p7g
PDBsum7p7g
PubMed35353987
UniProtP48730|KC1D_HUMAN Casein kinase I isoform delta (Gene Name=CSNK1D)

[Back to BioLiP]