Structure of PDB 7p7f Chain B

Receptor sequence
>7p7fB (length=292) Species: 9606 (Homo sapiens) [Search protein sequence]
LRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIE
SKIYKMMQGGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSL
KTVLLLADQMISRIEYIHSKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGL
AKKYRDARTHQHIPYRENKNLTGTARYASINTHLGIEQSRRDDLESLGYV
LMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVLCKGYPSEFATYL
NFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLK
3D structure
PDB7p7f Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes.
ChainB
Resolution1.96 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
2.7.11.26: [tau protein] kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 AMP B G18 I23 A36 K38 M82 L85 L135 I148 D149 G16 I21 A34 K36 M80 L83 L133 I146 D147
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7p7f, PDBe:7p7f, PDBj:7p7f
PDBsum7p7f
PubMed35353987
UniProtP48730|KC1D_HUMAN Casein kinase I isoform delta (Gene Name=CSNK1D)

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