Structure of PDB 7p3f Chain B

Receptor sequence
>7p3fB (length=147) Species: 100226 (Streptomyces coelicolor A3(2)) [Search protein sequence]
MHCPFCRHPDSRVVDSRTTDDGTSIRRRRQCPDCSRRFTTVETCSLMVVK
RSGVTEPFSRTKVINGVRKACQGRPVTEDALAQLGQRVEEAVRATGSAEL
TTHDVGLAILGPLQELDLVAYLRFASVYRAFDSLEDFEAAIAELRET
3D structure
PDB7p3f A nucleotide-sensing oligomerization mechanism that controls NrdR-dependent transcription of ribonucleotide reductases.
ChainB
Resolution3.31 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B R12 V13 S16 R17 R27 R12 V13 S16 R17 R27
BS02 dna B R26 R28 R37 R26 R28 R37
BS03 ATP B K50 R51 E56 F58 S59 K62 V63 T102 V105 K50 R51 E56 F58 S59 K62 V63 T102 V105
BS04 DTP B A70 V127 A70 V127
BS05 ZN B C3 C31 C34 C3 C31 C34
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0045892 negative regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:7p3f, PDBe:7p3f, PDBj:7p3f
PDBsum7p3f
PubMed35577776
UniProtO69980|NRDR_STRCO Transcriptional repressor NrdR (Gene Name=nrdR)

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