Structure of PDB 7p18 Chain B

Receptor sequence
>7p18B (length=557) Species: 157592 (Sterolibacterium denitrificans) [Search protein sequence]
TNTYDVIVVGSGAGAMLAAARAHDLGLSVLVVEKSDKYGGTSAVSGGAVW
IPNNSQMQIKDSFDEALTYLKAATQGLVAEDRLLAYLESAPQMVEYINAN
MTLQYFPCHRYPDYYQHLPGAKPGGRTMEPMLFDAALLGDEFANLRMAYT
GTLLMGKASMTATEAHVMLAKEPGWMLQVIKSLGRYYLDLPWRLKSRHDR
KRGLGNAMAAGLRHALLERKVPLWLNTPFESLITEGAENKRVTGIVVKRN
GQTLQLTARRGVVLGAGGFERNQQMREQYLPKPTNAAWSATPPHNTGDTI
RAAMDIGARAELMDWAWWVPSIHVPGEAAQTGLFAERNLPGCIVVNGKGQ
RFINEASPYLEFGAAMYENHARSGSAVPAWLIFDGKFRYNYPMGPLMPGQ
IQPDRKAWLGKVYWRDDTLEGLAKQIGVDAAGLKQSVELNNQYAQDGKDR
EFDKGGNVFDRYYGDYNVKPNPCLAPIGKPPYYAMRVDAGDIGTKGGLLT
DKDARVLDESDRPIEGLYCIGNNSASVMGKAYPGAGGTLGPAMTFGFRAA
NHIAASK
3D structure
PDB7p18 Structure, Mutagenesis, and QM:MM Modeling of 3-Ketosteroid Delta 1 -Dehydrogenase from Sterolibacterium denitrificans ─The Role of a New Putative Membrane-Associated Domain and Proton-Relay System in Catalysis.
ChainB
Resolution1.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.99.4: 3-oxosteroid 1-dehydrogenase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FAD B G14 G16 E37 K38 G44 T45 S46 V48 S49 G50 A52 P232 F233 A270 G271 H298 N299 D302 F338 I496 N526 G540 T542 L543 G10 G12 E33 K34 G40 T41 S42 V44 S45 G46 A48 P228 F229 A266 G267 H294 N295 D298 F334 I492 N522 G536 T538 L539
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
GO:0047571 3-oxosteroid 1-dehydrogenase activity
Biological Process
GO:0008202 steroid metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:7p18, PDBe:7p18, PDBj:7p18
PDBsum7p18
PubMed36625854
UniProtA9XWD7

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