Structure of PDB 7p11 Chain B

Receptor sequence
>7p11B (length=149) Species: 9606 (Homo sapiens) [Search protein sequence]
NNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSS
MKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEI
VIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFS
3D structure
PDB7p11 Structure-Guided Design of d-Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5KM B R45 Q47 R59 H65 R69 N79 W86 E89 Y141 G142 R40 Q42 R54 H60 R64 N74 W81 E84 Y136 G137
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding

View graph for
Molecular Function
External links
PDB RCSB:7p11, PDBe:7p11, PDBj:7p11
PDBsum7p11
PubMed34795863
UniProtO00214|LEG8_HUMAN Galectin-8 (Gene Name=LGALS8)

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