Structure of PDB 7ovg Chain B

Receptor sequence
>7ovgB (length=263) Species: 70601 (Pyrococcus horikoshii OT3) [Search protein sequence]
HMVKVGYIQMEPKILELDKNYSKAEKLIKEASKEGAKLVVLPELFDTGYN
FESREEVFDVAQQIPEGETTTFLMELARELGLYIVAGTAEKSGNYLYNSA
VVVGPRGYIGKYRKIHLFYREKVFFEPGDLGFKVFDIGFAKVGVMIAFDW
FFPESARTLALKGAEIIAHPANLVMPYAPRAMPIRALENRVYTITADRVG
EERGLKFIGKSLIASPKAEVLSIASETEEEIGVVEIDLNLARNKRLNDMN
DIFKDRREEYYFR
3D structure
PDB7ovg The structures of the C146A variant of the amidase from Pyrococcus horikoshii bound to glutaramide and acetamide suggest the basis of amide recognition.
ChainB
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ACM B E42 K113 F117 E120 A146 F147 N171 E43 K114 F118 E121 A147 F148 N172
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides

View graph for
Molecular Function
External links
PDB RCSB:7ovg, PDBe:7ovg, PDBj:7ovg
PDBsum7ovg
PubMed35439644
UniProtO58376

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