Structure of PDB 7oqh Chain B

Receptor sequence
>7oqhB (length=363) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
VVQPVAGILDVLDNYAFVRTSGYLPGPHDVYVSMNMVRKNGMRRGDAVTG
AVRVPRQKFNPLVRLDSINGGSVEDAKKRPEFGKLTPLYPNQRLRLETST
ERLTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQDIANAITRNNPECHL
MVVLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTSVAELAIERAKRLV
EQGKDVVVLLDSITRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAA
RNIEEGGSLTIIATAMVETGSTGDTVIFEEFKGTGNAELKLDRKIAERRV
FPAVDVNPSGTRKDELLLSPDEFAIVHKLRRVLSGLDSHQAIDLLMSQLR
KTKNNYEFLVQVS
3D structure
PDB7oqh Cryo-EM structure of transcription termination factor Rho from Mycobacterium tuberculosis reveals bicyclomycin resistance mechanism.
ChainB
Resolution3.32 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP B K356 G358 K359 T360 T361 F530 K127 G129 K130 T131 T132 F301
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0008186 ATP-dependent activity, acting on RNA
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0006353 DNA-templated transcription termination
GO:0006363 termination of RNA polymerase I transcription
Cellular Component
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7oqh, PDBe:7oqh, PDBj:7oqh
PDBsum7oqh
PubMed35140348
UniProtP9WHF3|RHO_MYCTU Transcription termination factor Rho (Gene Name=rho)

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