Structure of PDB 7onk Chain B

Receptor sequence
>7onkB (length=505) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]
SVRHIAIPAHRGLITDRNGEPLAVSTPVTTLWANPKELMTAKERWPQLAA
ALGQDTKLFADRIEQNAEREFIYLVRGLTPEQGEGVIALKVPGVYSIEEF
RRFYPAGEVVAHAVGFTDVDDRGREGIELAFDEWLAGVPGKRQVLKDRRG
RVIKDVQVTKNAKPGKTLALSIDLRLQYLAHRELRNALLENGAKAGSLVI
MDVKTGEILAMTNQPTYNPNNRRNLQPAAMRNRAMIDVFEPGSTVKPFSM
SAALASGRWKPSDIVDVYPGTLQIGRYTIRDVSRNSRQLDLTGILIKSSN
VGISKIAFDIGAESIYSVMQQVGLGQDTGLGFPGERVGNLPNHRKWPKAE
TATLAYGYGLSVTAIQLAHAYAALANDGKSVPLSMTRVDRVPDGVQVISP
EVASTVQGMLQQVVEAQGGVFRAQVPGYHAAGKSGTARKVRENAYRSLFA
GFAPATDPRIAMVVVIDEPSKAGYFGGLVSAPVFSKVMAGALRLMNVPPD
NLPTA
3D structure
PDB7onk Interaction Mode of the Novel Monobactam AIC499 Targeting Penicillin Binding Protein 3 of Gram-Negative Bacteria.
ChainB
Resolution1.73 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.4.16.4: serine-type D-Ala-D-Ala carboxypeptidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VL5 B E291 G293 S294 S349 Y409 S485 G486 T487 A488 R489 Y532 E240 G242 S243 S298 Y358 S434 G435 T436 A437 R438 Y474
Gene Ontology
Molecular Function
GO:0004180 carboxypeptidase activity
GO:0008658 penicillin binding
GO:0008955 peptidoglycan glycosyltransferase activity
GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity
Biological Process
GO:0000917 division septum assembly
GO:0006508 proteolysis
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0043093 FtsZ-dependent cytokinesis
GO:0051301 cell division
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7onk, PDBe:7onk, PDBj:7onk
PDBsum7onk
PubMed34356681
UniProtG3XD46|FTSI_PSEAE Peptidoglycan D,D-transpeptidase FtsI (Gene Name=ftsI)

[Back to BioLiP]