Structure of PDB 7okb Chain B

Receptor sequence
>7okbB (length=258) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence]
MSLIDPRAIIDPSARLAADVQVGPWSIVGAEVEIGEGTVIGPHVVLKGPT
KIGKHNRIYQFSSVGEDTPDLKYKGEPTRLVIGDHNVIREGVTIHRGTVQ
DRAETTIGDHNLIMAYAHIGHDSVIGNHCILVNNTALAGHVHVDDWAILS
GYTLVHQYCRIGAHSFSGMGSAIGKDVPAYVTVFGNPAEARSMNFEGMRR
RGFSSEAIHALRRAYKVVYRQGHTVEEALAELAESAAQFPEVAVFRDSIQ
SATRGITR
3D structure
PDB7okb Discovery of Novel UDP- N -Acetylglucosamine Acyltransferase (LpxA) Inhibitors with Activity against Pseudomonas aeruginosa .
ChainB
Resolution3.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.129: acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 VFZ B H118 A138 Q157 H118 A138 Q157
BS02 VFZ B V132 N133 S150 G151 M169 V132 N133 S150 G151 M169
Gene Ontology
Molecular Function
GO:0008780 acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity
GO:0016740 transferase activity
GO:0016746 acyltransferase activity
Biological Process
GO:0008610 lipid biosynthetic process
GO:0009245 lipid A biosynthetic process
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7okb, PDBe:7okb, PDBj:7okb
PDBsum7okb
PubMed34569791
UniProtA0A069Q726

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