Structure of PDB 7ocr Chain B

Receptor sequence

>7ocrB (length=675) Species: 575584 (Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841)

VLIFHGKPVHGAIFDMDGTMFDTERLRFQTLQQASQELIGQEFSHEYLMQ
CLGLSATTAEKLAQRLYKEIRKRADEMELEHIRKHGVPIKKGLVQVLERL
RKSGLRMAVATSSRRAIAEEYLINANVYKFFDVITCGDEVEQGKPHPEIF
LKAASQLHLDANQCLMFEDSENGLTSAHTSKGLTILLKDIKEPNDEMLEK
AHFYYDQMYDFLTDLDQFIPVMDMPEMQEPFPQSLNQLTVGIHGFGAIGG
GYIAQILSHWDGYTKPKRIIASTRNSLFREAVNAFGTYSIRYGQFSYDER
IENMSIVDSDNEQQMLEMYTHSSLIALCLPEQAIESESKIIAKGLYARFN
SQEPLTFLIILNKVGAKYLVMKHLKEALLELTNDEDVTEHILKEHYFCDT
VVNRMVSKLSNQNLYRQLRIKHNFLEQHLEDVEEDCNKLTPDQLNQASIY
VDNMRRNFQPGHILQSMDLILFHSETDMPIYVEKGSPLLEKLRQVVLVDQ
ITDIQLIKNRLWNGVHAMLAWYASLMGYESIGVAMGDHLVKAFAENLIAE
VKQGLAIVLPNYAKDLDRMSQSFLDSCEYAFKDPCQRVARDPLRKLNHNE
RVMASIAVNIRHDLPYKNLLKGAALGYAYAIQFLEIEETKAVEHLQQQIQ
NLDLSTAQRRQLEAELVQLIQYLFS

3D structure

• PDB: 7ocr Unidirectional mannitol synthesis of Acinetobacter baumannii MtlD is facilitated by the helix-loop-helix-mediated dimer formation.
• Chain: B
• Resolution: 2.6 Å

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NDP	B	G251 G253 A254 I255 T280 R281 L336 P337 A340 L373 N374 V418 R606 R609	G244 G246 A247 I248 T273 R274 L329 P330 A333 L361 N362 V406 R587 R590
BS02	F6R	B	N374 N415 K527 N532 H535 R606 R609 R613 K614 R620	N362 N403 K508 N513 H516 R587 R590 R594 K595 R601
BS03	MG	B	D16 D18 D176	D15 D17 D169

Gene Ontology

Molecular Function

• GO:0000166 nucleotide binding
• GO:0016491 oxidoreductase activity
• GO:0016787 hydrolase activity
• GO:0046872 metal ion binding

External links

• PDB: RCSB:7ocr, PDBe:7ocr, PDBj:7ocr
• PDBsum: 7ocr
• PubMed: 35363566
• UniProt: D0C7J2