Structure of PDB 7o56 Chain B

Receptor sequence
>7o56B (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
GKLRQWLIDQIDSGKYPGLVWENEEKSIFRIPWKHAGKQDYNREEDAALF
KAWALFKGKFREGIDKPDPPTWKTRLRCALNKSNDFEELVERSQLDISDP
YKVYRIVPE
3D structure
PDB7o56 Phosphorus and sulfur SAD phasing of the nucleic acid-bound DNA-binding domain of interferon regulatory factor 4.
ChainB
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B W54 H56 A57 K94 R98 K103 W33 H35 A36 K73 R77 K82
BS02 dna B G22 L24 H56 G58 W74 K78 K80 R96 C99 A100 K103 G1 L3 H35 G37 W53 K57 K59 R75 C78 A79 K82
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7o56, PDBe:7o56, PDBj:7o56
PDBsum7o56
PubMed34196610
UniProtQ15306|IRF4_HUMAN Interferon regulatory factor 4 (Gene Name=IRF4)

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