Structure of PDB 7o0q Chain B

Receptor sequence
>7o0qB (length=243) Species: 9606 (Homo sapiens) [Search protein sequence]
YCQHFVDTGHRPQNFIRDVELIRLKDELIAKSNTPPMYLQADIEAFDIRE
LTPKFDVILLEPPLEEYYRETKCWTWDDIMKLEIDEIAAPRSFIFLWCGS
GEGLDLGRVCLRKWGYRRCEDICWIKTNKNNPGKTKTLDPKAVFQRTKEH
CLMGIKGTVDIDLIITEEPEIGNIEKPVEIFHIIEHFCLGRRRLHLFGRD
STIRPGWLTVGPTLTNSNYNAETYASYFSAPNSYLTGCTEEIE
3D structure
PDB7o0q Crystal structure of the human METTL3-METTL14 complex bound to Compound 12 (ADO_AD_066)
ChainB
Resolution2.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 MG B D157 H332 H336 D26 H182 H186
External links
PDB RCSB:7o0q, PDBe:7o0q, PDBj:7o0q
PDBsum7o0q
PubMed
UniProtQ9HCE5|MET14_HUMAN N6-adenosine-methyltransferase non-catalytic subunit (Gene Name=METTL14)

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