Structure of PDB 7nzi Chain B

Receptor sequence
>7nziB (length=206) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
WADDFLAENADIAISNPADYKGKWNTVFGNDNPIHIEVGTGKGQFISGMA
KQNPDINYIGIELFKSVIVTAVQKVKDSEAQNVKLLNIDADTLTDVFEPG
EVKRVYLNFSDPWPKKRHEKRRLTYSHFLKKYEEVMGKGGSIHFKTDNRG
LFEYSLKSFSEYGLLLTYVSLDLHNSNLEGNIMTEYEEKFSALGQPIYRA
EVEWRT
3D structure
PDB7nzi Structural model of the M7G46 Methyltransferase TrmB in complex with tRNA.
ChainB
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.33: tRNA (guanine(46)-N(7))-methyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SAH B G46 T47 E69 D96 A97 N115 F116 T191 Y193 G39 T40 E62 D89 A90 N108 F109 T184 Y186
Gene Ontology
Molecular Function
GO:0008168 methyltransferase activity
GO:0008176 tRNA (guanine(46)-N7)-methyltransferase activity
Biological Process
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0030488 tRNA methylation
GO:0032259 methylation
GO:0036265 RNA (guanine-N7)-methylation
GO:0106004 tRNA (guanine-N7)-methylation
Cellular Component
GO:0043527 tRNA methyltransferase complex

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Molecular Function

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Cellular Component
External links
PDB RCSB:7nzi, PDBe:7nzi, PDBj:7nzi
PDBsum7nzi
PubMed34006170
UniProtO34522|TRMB_BACSU tRNA (guanine-N(7)-)-methyltransferase (Gene Name=trmB)

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